2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W782193
    Sulcatone-d5 55320-91-7 98%
    Sulcatone-d5 (6-Methyl-5-hepten-2-one-d5) is the deuterium labeled Sulcatone (HY-W010435). Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis.
    Sulcatone-d5
  • HY-W782550
    FK-352 143881-08-7 98%
    FK-352 is a selective adenosine A1 receptor antagonist. FK-352 significantly improves intradialytic hypotension in chronic hemodialysis. FK-352 can be used for the study of intradialytic hypotension.
    FK-352
  • HY-W783254
    C18 LPA 799279-67-7 98%
    C18 LPA (PA(18:0e/0:0)) is a water-soluble phospholipid that functions as a signaling molecule, influencing various cellular responses through G protein-coupled receptors (GPCRs). It is known to promote smooth muscle contraction, cytoskeletal rearrangement, and chemotaxis, while also playing a role in neurotransmitter release, cell proliferation, platelet aggregation, and Ca2+ mobilization. Elevated levels of C18 LPA in human plasma are associated with ovarian cancer and atherosclerosis, suggesting its potential as a biomarker for ovarian cancer.
    C18 LPA
  • HY-W791754
    Paeonolsilate sodium 827610-11-7 98%
    Paeonolsilate (sodium) can inhibit ox-LDL-induced macrophage foam cell formation and inflammation in atherosclerosis. Paeonolsilate (sodium) inhibits NF-κB activation and oxidative stress response induced by ox-LDL. Paeonolsilate (sodium) can be studied in anti-atherosclerosis research.
    Paeonolsilate sodium
  • HY-W802239
    Asparaginate calcium 39162-75-9 98%
    Asparaginate calcium is a calcium2+ salt of asparaginate and anion/zwitterion form of aspartic acid. Asparaginate calcium is a calcium supplement and an antiarrhythmic active substance. Asparaginate calcium can be used for the research of arrhythmia.
    Asparaginate calcium
  • HY-W854549
    Heparin pentasaccharide 104993-28-4 98%
    Heparin pentasaccharide (Fondaparinux) is a chemically synthesized selective factor Xa inhibitor with anticoagulant activity. Heparin pentasaccharide can be utilized in researches related to venous thromboembolic events.
    Heparin pentasaccharide
  • HY-W879307
    CP-201 2460280-41-3 98%
    CP-201 is a 1,4-Naphthoquinone (HY-W015490) derivative with antiplatelet and antithrombotic activities. CP-201 shows concentration-dependent inhibitory effects on platelet aggregation induced by collagen and thrombin, with IC50 values of 4.1 and 4.6 μM, respectively. CP-201 displays a potent protective effect on pulmonary thrombosis in mice. CP-201 can be used for antithrombotic research.
    CP-201
  • HY-W923483
    C16-18:1 PC 95403-34-2 99%
    C16-18:1 PC (1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine), also known as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of the platelet-activating factor (PAF) family of glycerophospholipids and serves as a pro-inflammatory lipid mediator with diverse biological and pharmacological effects; it features a mono-ether structure with an oleoyl chain (18:1) ester-linked at the sn-2 position and a hexadecyl chain (16:0) ether-linked at the sn-1 position.
    C16-18:1 PC
  • HY-W950003
    (Rac)-Finerenone-d5 2917530-31-3
    (Rac)-Finerenone-d5 ((Rac)-BAY 94-8862-d5) is the deuterium labeled (Rac)-Finerenone (HY-111372A). (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
    (Rac)-Finerenone-d5
  • HY-W990281
    B-GYKI-38233 hydrochloride 100751-82-4
    B-GYKI-38233 hydrochloride (Restacorin) is a sodium channel blocker used in antiarrhythmic research.
    B-GYKI-38233 hydrochloride
  • HY-Y0366S4
    Lauric acid-13C-1 287100-78-1 98%
    Lauric acid-13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-13C-1
  • HY-Y0682AR
    Ethylenediaminetetraacetic acid disodium dihydrate (Standard) 6381-92-6 98%
    Ethylenediaminetetraacetic acid (disodium dihydrate) (Standard) is the analytical standard of Ethylenediaminetetraacetic acid (disodium dihydrate). This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research[4].
    Ethylenediaminetetraacetic acid disodium dihydrate (Standard)
  • HY-Y0682S2
    Ethylenediaminetetraacetic acid-d4 15251-22-6
    Ethylenediaminetetraacetic acid-d4 (EDTA-d4) is the deuterium labeled Ethylenediaminetetraacetic acid (HY-Y0682). Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research.
    Ethylenediaminetetraacetic acid-d4
  • HY-Y0842S2
    Formamide-13C,15N 285977-74-4 99.4%
    Glycine-13C,15N is the 13C and 15N labeled Glycine (HY-Y0842). Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. It induces apoptosis by promoting the formation of cyclic nucleotides and the phosphorylation and dephosphorylation processes of nucleotides, making it useful in cancer research. Formamide can also be used as a decalcifying agent for rat cardiac cells. Additionally, formamide is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers..
    Formamide-13C,15N
  • HY-Y0842S3
    Formamide-15N 1449-77-0 99.50%
    Formamide-15N is the 15N labeled Formamide (HY-Y0842). Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. Formamide can also be used as a decalcifying agent for rat cardiac cells. Additionally, formamide is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers.
    Formamide-15N
  • HY-Y0842S4
    Formamide-d1 35692-88-7 98%
    Formamide-d1 is the deuterium labeled Formamide (HY-Y0842). Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. Formamide can also be used as a decalcifying agent for rat cardiac cells. Additionally, formamide is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers.
    Formamide-d1
  • HY-Y0842S5
    Formamide-d2 35645-04-6 98%
    Formamide-d2 is the deuterium labeled Formamide (HY-Y0842). Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. Formamide can also be used as a decalcifying agent for rat cardiac cells. Additionally, formamide is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers.
    Formamide-d2
  • HY-100490BR
    Rilmenidine phosphate (Standard) 85409-38-7
    Rilmenidine (phosphate) (Standard) is the analytical standard of Rilmenidine (phosphate). This product is intended for research and analytical applications. Rilmenidine phosphate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine phosphate is an alpha 2-adrenoceptor agonist. Rilmenidine phosphate induces autophagy. Rilmenidine phosphate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+/H+ antiport. Rilmenidine phosphate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells .
    Rilmenidine phosphate (Standard)
  • HY-101981S1
    Uridine 5'-monophosphate-15N2,d11 dilithium 98%
    Uridine 5'-monophosphate-15N2,d11 (5'- Uridylic acid-15N2,d11) dilithium is deuterium and 15N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
    Uridine 5'-monophosphate-15N2,d11 dilithium
  • HY-101981S3
    Uridine 5'-monophosphate-13C9,15N2 dilithium 2483830-55-1 98%
    Uridine 5'-monophosphate-13C9,15N2 (5'- Uridylic acid-13C9,15N2) dilithium is 13C and 15N-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
    Uridine 5'-monophosphate-13C9,15N2 dilithium
Cat. No. Product Name / Synonyms Application Reactivity